Metabolomix+ Profile


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The Metabolomix+ provides analysis of key nutritional biomarkers using non-invasive first morning void (FMV) urine collection with optional add-on bloodspot finger stick and buccal swab.  Common clinical indications for testing include:

  • Mood disorders1,2
  • Mitochondrial dysfunction3
  • Fatigue4
  • Chronic stress5
  • Inflammation6

The Metabolomix+ Profile report categorizes results into several metabolic areas

  • Organic Acids (urine)
    • Malabsorption and Bacterial/ Yeast Dysbiosis Markers are metabolites produced by the gastrointestinal microbiome
    • Cellular Energy & Mitochondrial Metabolites are biomarkers of carbohydrate and fatty acid metabolism, and the citric acid (Kreb’s) cycle
    • Neurotransmitter Metabolites are downstream byproducts of epinephrine, norepinephrine, serotonin and dopamine
    • Vitamin Markers are specific analytes used to assess functional levels of vitamin cofactors
    • Toxin & Detoxification Markers relate to certain toxic metabolites and the body’s detoxification capacity
    • Oxalate Markers relate to kidney stone formation, oxidative stress and metabolic dysfunction
  • Amino Acids (urine)
    • Essential Amino Acids must be derived from dietary sources
    • Nonessential Amino Acids are synthesized by the body
    • Intermediary Metabolites are byproducts of amino acid metabolism
      • B Vitamin Markers are involved in biochemical reactions that specifically require B vitamins
      • Urea Cycle Markers are byproducts associated with nitrogen (ammonia) detoxification
      • Glycine/Serine Metabolites are involved in the serine-to-choline pathway and the methylation pathways
    • Dietary Peptide Related Markers can indicate incomplete protein breakdown and meat intake
  • Oxidative Stress Markers (urine) include the oxidative damage markers lipid peroxides and 8-OHdG
  • Essential Fatty Acids (Bloodspot)
  • Nutrient and Toxic Elements (urine)  assesses  15 mineral and  20 toxic elements